Scientific Computing Seminar

Date:

Friday, May 6, 2005

Time:

1:00pm-2:00pm

Location:

50A-5132

Seminar Speaker:

Jack Schonbrun
University of Washington

Title:

High Resolution Protein Molding

Abstract:

The computational modeling of protein structure is beginning to approach experimental accuracy. A potential function based largely on van der Waals interactions and hydrogen bonding has led to theoretical structures in design, docking, and de novo fold prediction that have been correct in high-resolution details. These results suggest that computational structural biology is on the verge of becoming a useful tool for general research. The current bottleneck is the computational effort required during the conformational search process. Access to large scale computing facilities may allow for immediate application of these methods to scientific problems in biology.

Sponsor of Seminar:

Silvia Crivelli

Scientific Computing

Contact Esmond G. Ng EGNg@lbl.gov